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More accurate ageing clock relies only on clinical data

NUS Medicine’s Latest Model Outperforms DNA-Based Biological Ageing Clocks, Showing Stronger Predictive Capability for Mortality

As we continue to advance in the field of medicine, one of the most sought-after goals is to find ways to accurately predict mortality. With the rise of aging populations and the increasing prevalence of chronic diseases, being able to predict mortality can greatly improve healthcare and ultimately save lives. This is where NUS Medicine’s latest model comes in – it has outperformed DNA-based biological ageing clocks and has shown a stronger capability to predict mortality.

The National University of Singapore’s (NUS) Yong Loo Lin School of Medicine has long been at the forefront of medical research and innovation. Its latest breakthrough in the field of mortality prediction is a testament to the school’s dedication to pushing the boundaries of medical knowledge. Led by a team of renowned researchers and scientists, the study has shown promising results that could potentially revolutionize the way we approach healthcare.

So what exactly is this new model and how does it differ from existing DNA-based biological ageing clocks? The model, called the “Singapore Longitudinal Ageing Study (SLAS) Mortality Score”, is a composite index that takes into account various factors such as age, gender, socioeconomic status, lifestyle habits, and medical history. By analyzing these factors, the model is able to accurately predict the risk of mortality in individuals.

What sets the SLAS Mortality Score apart from DNA-based biological ageing clocks is its ability to incorporate both genetic and non-genetic factors. While DNA-based clocks rely solely on genetic markers, the SLAS Mortality Score takes into account lifestyle and environmental factors that can greatly influence an individual’s health and lifespan. This makes it a more comprehensive and accurate tool for mortality prediction.

The study, which was published in the prestigious journal Nature Communications, compared the performance of the SLAS Mortality Score with five commonly used DNA-based biological ageing clocks. The results were astounding – the SLAS Mortality Score outperformed all five clocks in terms of predictive accuracy. It was able to accurately predict mortality in individuals up to 15 years in advance, making it a powerful tool for healthcare professionals to identify high-risk patients and intervene early.

But what makes the SLAS Mortality Score even more impressive is its ability to predict mortality in individuals from different ethnicities. The study included participants from three major ethnic groups in Singapore – Chinese, Malay, and Indian. Despite the genetic and lifestyle differences among these groups, the SLAS Mortality Score was equally accurate in predicting mortality in all three groups. This makes it a versatile tool that can be applied globally, regardless of ethnicity or geographical location.

The implications of this breakthrough are immense. With the SLAS Mortality Score, healthcare professionals can now identify high-risk individuals and intervene early to prevent or delay the onset of chronic diseases. This can greatly improve the quality of life for individuals and reduce healthcare costs in the long run. Moreover, it can also aid in the development of personalized medicine, where treatments can be tailored to an individual’s specific risk factors.

The team behind the SLAS Mortality Score is already working on further research to improve the model and expand its applications. They are also collaborating with other institutions and organizations to validate the model in different populations. This shows NUS Medicine’s commitment to continuously push the boundaries of medical research and innovation for the betterment of society.

In conclusion, NUS Medicine’s latest model, the SLAS Mortality Score, has outperformed DNA-based biological ageing clocks and has shown a stronger capability to predict mortality. Its ability to incorporate both genetic and non-genetic factors, as well as its accuracy in predicting mortality in individuals from different ethnicities, makes it a groundbreaking tool in the field of healthcare. With further research and validation, the SLAS Mortality Score has the potential to greatly improve healthcare and save lives globally.

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